XIII SBBN Congress and 20th IUPAB Congress, Foz do Iguaçu, 26-30/10/2020

Since 2017, the Brazilian Society on Nuclear Biosciences (SBBN) is affiliated to the International Union for Pure and Applied Biophysics (IUPAB).

The XIII SBBN Congress will be held in parallel with the 20th International Congress of IUPAB, the 45th Annual Brazilian Biophysical Society (SBBf) Meeting, and the 49th Annual Brazilian Biochemistry and Molecular Biology Society (SBBq) Meeting. All participants may attend these four events paying only one inscription.

The Annual Meetings of SBBf and SBBq are two of the most traditional events within the Brazilian scientific community. They have been the forum of choice for presentations and discussions regarding the state of the art in biologically relevant phenomena, as well as their social benefits. Science policy, integration with other segments of the economy and outreach activities have also been among the main focuses of these events.

The SBBN Congress represents the opportunity for exchanging experiences about our common impacting problems, as Bioethics, animal experimentation and alternative methods, biosafety and radiation protection, drug registration and interactions with regulatory health agencies and research ethics committees, environmental biological effects of human activities and sciences education. Themes that actually have developed at isolated way may be integrated. The current frontiers in Biological Sciences demand an interface among disciplines of Biology, Chemistry and Physics to achieve new paradigms on applied ionizing and non-ionizing radiation as well as nanobiotechnologies, seeking for Individualized Medicine.

SBBN Keynote Lectures (60 min)
• Biomolecules and drug development – speaker to be confirmed
• Novel cyclotron radioisotopes and novel radiopharmaceuticals (Suzanne Lapi (University of Alabama at Birmingham, Alabama, USA)
• Alpha radionuclides therapy and bone marrow dosimetry (George Sgouros, Johns Hopkins Medicine Department of Radiology and Radiological Science, Baltimore, USA)
• Convention on assistance in the case of a nuclear accident or radiological emergency: international experiences (Ambassador Marcel Biato (Permanent Brazilian mission representative at IAEA, Vienna)-to be confirmed

SBBN Symposia (120 min)

Biomaterials and molecular imaging techniques
• Total-Body Radiotracer Pharmacokinetics and Molecular Imaging (Simon R. Cherry, University of California, Davis, USA)
• Molecular imaging for research in Oncology (Carlos Buchpiguel, Professor and Director of the Nuclear Medicine Center, Sao Paulo University Medical School, Brazil)

Molecular Imaging in Neurosciences
• New trends in PET radiopharmaceuticals for neurodegenerative diseases (Eduardo Savio, Uruguayan Centre for Molecular Imaging, Montevideo, Uruguay)
• Pericytes and the intersection between tissue regeneration and pathology (Alexander Birbrair, Federal University of Minas Gerais, Belo Horizonte, Brazil)
• PET/CT/MRI fusion images showing cranial and peripheral nerve involvement in neurolymphomatosis (Lauro Wichert-Ana, Ribeirão Preto Medical School, University of São Paulo, Brazil)

The new paradigms in Cellular Biology and Precision Medicine for prostate cancer
• Targeting androgen receptor signaling in prostate cancer (Hernandes Carvalho, UNICAMP; FESBE President, Campinas, Brazil)
• Alpha or beta emitters for prostate cancer treatment? (George Sgouros, John Hopinks, USA)
• Prostate cancer treatments and follow up: Brazilian experiences (Juliano Cerci, Brazilian Society on Nuclear Medicine President, Curitiba, Brazil)

Radiobiology and Radiotherapy
• Radiation interaction and response from cells and tissues (Dunstana Melo, Melohill Tech., Washington, USA)
• Dose fractionation in Radiotherapy patients (Helena Segreto, Medical School, São Paulo Federal University and Brazilian Society on Radiotherapy, São Paulo, Brazil)
• Development of three-dimensional cellular culture system for testing of biological effects of radiations in tumoral and non-tumoral models (Daniel Perez, Biotechnology Center, Nuclear and Engineering Research Institute, IPEN/CNEN, São Paulo, SP)

Cancer epidemiology and radiation exposures
• Thyroid Cancer Following Childhood Low-Dose Radiation Exposure (Lene Veiga, National Cancer Institute, Division of Cancer Epidemiology and Genetic, Washington, USA)
• Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries (Maria Paula Curado, A.C. Camargo Center, São Paulo, Brazil)

Challenges in clinical studies with ionizing radiation
• Education and individual capabilities in the multidisciplinary teams for developing non-clinical and clinical studies (Ana Maria Marques da Silva, PUC-RS Physics Institute, Porto Alegre, Brazil)
• The reference hospitals, the equipment state-of-the art and the regional inequities (Jorge Wagner Esteves da Silva, National Cancer Institute, Health Ministry, Rio de Janeiro, Brazil)

Nuclear accidents and the environmental and radiological impact
• Nuclear reactors exposures scenarios (Marcos Amaral, SBPR, Brazil)
• Nuclear accidents and decision making in the perspective of environmental radiological releases (Matthew Healy, Cranfield University, UK)
• Biological effects of acute exposures and experience in supporting victims in nuclear or radiological accidents (Carlos Eduardo Brandão Mello, Rio de Janeiro Federal State University, Rio de Janeiro, Brazil)

IUPAB-SBBN Symposium: Nanobiotechnology. Chair: Valtencir Zucolotto (IFSC-USP, Brazil)

IUPAB-SBBN Symposium: Biophotonics. Chair: to be confirmed.

IUPAB plenary lectures invited speakers:

Richard Henderson, MRC Labs, Cambridge, UK – molecular biologist and biophysicist and pioneer in the field of electron microscopy of biological molecules. He shared the Nobel Prize in Chemistry in 2017 with Jacques Dubochet and Joachim Frank.

Michael Levitt, Stanford University – biophysicist and a professor of structural Biology. He received the 2013 Nobel Prize in Chemistry, together with Martin Karplus and Arieh Warshel, for “the development of multiscale models for complex chemical systems.

Greg Winter, MRC Cambridge, UK, is credited with inventing techniques to both humanise (1986) and, later, to fully humanise using phage display, antibodies for therapeutic uses. He has founded several companies to exploit this technology for therapeutic uses. He received the Nobel Prize for Chemistry in 2018 along with George Smith and Frances Arnold

Angela Gronenborn, Ph.D. in physical chemistry (University of Cologne, Germany). She did postdoctoral work with protein NMR pioneer James Feeney at the National Institute for Medical Research in London. Since 2004, she is the Department of Structural Biology Chief in University of Pittsburgh.

Ohara Augusto is Full Professor of Biochemistry at Universidade de São Paulo, Brazil. Her research interests are focused on kinetics and mechanisms of redox enzymes, oxidant and antioxidant mechanisms, infection and inflammation. She is member of the Brazilian Academy of Science, of the Third World Academy of Sciences and is Fellow of the Society for Redox Biology and Medicine.

Ramon Latorre is Full professor of Neuroscience Institute from University of Valparaiso, Chile and Director of Interdisciplinary Center of Neuroscience of Valparaiso. His research interests are focused on understanding how the protein domains involved in sensing stimuli (sensors) and opening the pore (gates) communicate. He is member of Latin America Science Academy Council and Foreign Member of National Academy of Sciences, USA.

SBBN international invited speakers:

Dunstana Melo, Ph.D. in Biophysics from the Federal University of Rio de Janeiro, Brazil. Melohill Technology LLC President. She has experience in radiation protection, dosimetry, biokinetics, and biological effects of internally deposited radionuclides and methods for removing radionuclides from the body (decorporation). She has served on the National Council on Radiation Protection and Measurements (NCRP) and on the International Commission on Radiological Protection (ICRP) from 2006 to present.

Eduardo Savio, PhD in Chemistry. Director in Research and Development, Biomedical and Chemical Deparments, Uruguayan Centre for Molecular Imaging (CUDIM), Montevideo, Uruguay.

George Sgouros, PhD in Physics, Cornell University, USA. Professor at the Johns Hopkins Medicine Departments: Radiology and Radiological Science, Radiation Oncology and collaborator at the Johns Hopkins Kimmel Cancer Center. He is the director of the Radiopharmaceutical Dosimetry Section, Nuclear Medicine and Molecular Imaging Division. Society on Nuclear Medicine and Molecular Imaging Saul Hertz Award 2017 for outstanding achievements and contributions in radionuclide therapy.

Lene Holanda Sadler Veiga: PhD in Public Health/Epidemiology (National School in Public Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil). She is staff scientist in the National Cancer Institute/Division of Cancer Epidemiology and Genetic, Washington DC, USA.

Matthew J F Healy, senior research, Cranfield University, UK. International consultancy activities have included methods and technologies, decision support following the Fukushima accident, performing biological, chemistry, radiological and nuclear vulnerability assessments, independent requirements capture and assessing the cost of recovering from terrorism.

Simon Cherry, PhD in Biomedical Engineering, Professor at the University of California, Davis, USA. The Cherry Lab focuses on molecular imaging using positron emission tomography (PET) scanning. The team is currently studying pathologic processes that involve multiple organs systems or the entire body, the EXPLORER project, a collaboration with several colleagues to develop the world’s first total-body PET scanner. In 2018, he received the Paul C. Aebersold Award for outstanding achievement in basic nuclear medicine science.

Susanne Lapi, PhD in Chemistry. She is the Cyclotron Facility and Radiochemistry Laboratory and the Division of Advanced Medical Imaging Research Director and Associate Professor, Department of Radiology and Chemistry, at the University of Alabama at Birmingham. She is member of the International Society of Radiopharmaceutical Sciences (ISRS) Council.

SBBN Brazilian invited speakers:

Alexander Birbrair: Professor adjunto do Departamento de Patologia do Instituto de Ciências Biológicas da Universidade Federal de Minas Gerais, membro da Comissão Interna de Biosseguranca (CIBIO) e Vice-coordenador do Biotério do Departamento de Patologia. Membro Afiliado da Academia Brasileira de Ciências (ABC) e membro da Global Young Academy. Graduado em Biomedicina pela Universidade Estadual de Santa Cruz (UESC), doutorado em Neurociência pela Wake Forest University, Carolina do Norte, USA e pós-doutorado em Biologia Celular no Albert Einstein School of Medicine em Nova York, USA.

Ana Maria Marques da Silva: Bacharel, mestre e doutora em Física pela USP e pós-doutorado na KU Leuven (Bélgica). Professora titular Programa de Pós-Graduação em Engenharia Elétrica e em Gerontologia Biomédica da PUCRS, coordena o Núcleo de Pesquisa em Imagens Médicas e é pesquisadora do Instituto do Cérebro do RS (InsCer). Coordena o Programa de Residência em Física Médica do Hospital São Lucas da PUC-RS.

Carlos Alberto Buchpiguel: Graduação em Medicina pela Faculdade de Medicina da PUC-SP, doutorado em Radiologia pela Faculdade de Medicina da USP e fellowship em Medicina Nuclear no Departamento de Radiologia do Hospital da Universidade da Pensilvânia, USA. Professor Titular do Departamento de Radiologia e Oncologia da FM-USP, Diretor do Serviço de Medicina Nuclear e Imagem Molecular do Instituto de Radiologia do HC-FM-USP.

Carlos Eduardo Brandão Mello: Graduação em Medicina pela UNIRIO, Mestrado em Gastroenterologia pela UFRJ, Doutorado em Gastroenterologia pela UNIFESP e Livre Docência em Clínica Médica e Gastroenterologia pela UNIRIO. Professor Titular de Clínica Médica/Gastroenterologia da Escola de Medicina e Cirurgia do Rio de Janeiro da UFRJ. Coordena a Pós-Graduação em Gastroenterologia da Escola de Medicina e Cirurgia do Rio de Janeiro, Chefe da Unidade de Doenças do Fígado do Hospital Universitário Gaffrée e Güinle e Professor Adjunto da Faculdade de Medicina da UFRJ. Participou do atendimento médico as vítimas do Acidente Radioativo de Goiânia, com publicações exclusivas nesta particular área do conhecimento médico.

Helena Regina Comodo Segreto: Professora associada do Departamento de Oncologia Clínica e Experimental da UNIFESP. Doutorado em Medicina (Hematologia) pela UNIFESP e pós-doutorado pela Harvard Medical School. Sócia fundadora da Sociedade Brasileira de Radioterapia e da Asociación Ibero Latinoamericana de Terapia Radiante Oncológica., membro da Sociedade Brasileira de Hematologia e Hemoterapia e da Radiation Research Society.

Hernandes Faustino de Carvalho: Possui graduação em Ciências Biológicas, mestrado em Biologia Celular e doutorado em Bioquímica pela Universidade Estadual de Campinas (UNICAMP). É professor titular da UNICAMP. Foi Presidente da Sociedade Brasileira de Biologia Celular (2006-2008 e 2014-2016). É Secretário Geral da Federação Internacional de Biologia Celular (IFCB) desde 2008. Presidente da Federação das Sociedades de Biologia Experimental (2017-2019). Foi membro do CA-BM do CNPq, é coordenador do INCT-INFABIC e bolsista produtividade 1A do CNPq.

Jorge Wagner Esteves da Silva: Bacharelado em Física pela UERJ, mestrado e doutorado em Engenharia Nuclear pela UFRJ. É físico do Instituto Nacional de Câncer, e foi professor visitante da UERJ e professor colaborador do Instituto de Radioproteção e Dosimetria. Tem experiência em Engenharia Nuclear, Física Médica e Inteligência Artificial.

Juliano Julio Cerci: Graduação em Medicina pela Pontifícia Universidade Católica do Paraná, residência médica em medicina nuclear e especialização em Radiologia na Universidade de São Paulo, doutorado em Radiologia pela Faculdade de Medicina da Universidade de São Paulo. É diretor do Serviço de PET/CT da Quanta diagnóstico e Terapia e Presidente da Sociedade Brasileira de Medicina Nuclear.

Lauro Wichert Ana: Professor Associado do Centro de Ciências das Imagens e Física Médica da Faculdade de Medicina de Ribeirão Preto (FMRP-USP). Graduação em Medicina pela Universidade Federal de Uberlândia (UFU), Residência Médica em Neurologia pelo Hospital das Clínicas da FMRP-USP, Especialização em Neurofisiologia Clínica pelo HC-FMRP-USP, Especialização em Medicina Nuclear pelo HC-FMRP-USP e Mestrado e Doutorado em Ciências Médicas (Neurologia) pela FMRP-USP. Coordenador e Supervisor da Seção de Medicina Nuclear do Hospital das Clínicas, orientador do Programa de Clínica Médica e de Bioengenharia do FMRP-USP.

Maria Paula Curado: Medical doctor (Goias Federal Univesity), PhD in Oncology (Hospital do Câncer – A. C. Camargo, São Paulo, Brazil). Researcher and professor in the A.C.Camargo Cancer Center, São Paulo, Brazil. Researcher collaborator in the CONCORD-2 Global Programme, the London School of Hygiene & Tropical Medicine, the Union for International Cancer Control (UICC), endorsed by 39 national and international agencies, including WHO EURO, OECD and World Bank.